I will demonstrate how one can realize Cascade inflation in M-theory. Cascade inflation is a realization of assisted inflation which is driven by non-perturbative interactions of N M5-branes. Its power spectrum possesses three distinctive signatures: a decisive power suppression at small scales, oscillations around the scales that cross the horizon when the inflaton potential jumps and stepwise decrease in the scalar spectral index. All three properties result from features in the inflaton potential. The features in the inflaton potential are generated whenever two M5-branes collide with the boundaries. The derived small-scale power suppression serves as a possible explanation for the dearth of observed dwarf galaxies in the Milky Way halo. The oscillations, furthermore, allow to directly probe M-theory by measurements of the spectral index and to distinguish cascade inflation observationally from other string inflation models.