The PAMELA satellite-borne experiment was launched from the Baikonur cosmodrome on the 15th of June 2006. It has been collecting data since July 2006. The instrument is composed of a silicon-microstrip magnetic spectrometer, a time-of-flight system, a silicon-tungsten electromagnetic calorimeter, an anticoincidence system, a shower tail counter scintillator and a neutron detector. The primary scientific goal is the measurement of the antiproton and positron energy spectrum in order to search for exotic sources, such as dark matter particle annihilations. PAMELA is also searching for primordial antinuclei (anti-helium), and testing cosmic-ray propagation models through precise measurements of the energy spectra of light nuclei and their isotopes. Moreover, PAMELA is investigating phenomena connected with solar and earth physics. The first results obtained in the explored research fields and in particular for antiproton-proton and positron-electron ratios will be presented.