For nearly the past century, the nature of dark matter in the Universe has puzzled astronomers and physicists. During the next decade, experiments will determine if a substantial amount of the dark matter is in the form of non-baryonic, Weakly-Interacting Massive Particles (WIMPs). In this talk I will discuss and interpret modern limits on WIMP dark matter from a variety of complementary methods. I will show that we are just now obtaining sensitivity to probe the parameter space of cosmologically-predicted WIMPs created during the earliest epoch in the Universe. I will discuss the science to extract from a positive signal in different experiments, and the prospects for an era of dark matter astrophysics.